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The SOUL trial (Semaglutide Cardiovascular Outcomes Trial) was a randomized, double-blind, placebo-controlled cardiovascular outcomes trial that enrolled 9,650 patients aged 50 years or older with
25.55
At ADA 2025, the SOUL trial revealed that oral semaglutide (Rybelsus) reduced the risk of major cardiovascular events—like heart attack, stroke, and CV death—by 14% over ~4 years in type 2 diabetes
29.93
Journal club: SOUL Study – CVOT for Oral Semaglutide Full Title: Cardiovascular Outcomes Trial of Oral Semaglutide in Subjects with Type 2 Diabetes กองอายุรกรรม รพ พระมงกุฎเกล้า
21.18
Oral Semaglutide and Cardiovascular Outcomes in People With Type 2 Diabetes, According to SGLT2i Use: Prespecified Analyses of the SOUL Randomized Trial
23.71
Trial Scorecard: SOUL
29.95
Effect of Oral Semaglutide on Cardiovascular Outcomes in Type 2 Diabetes by Extent of Vascular Disease
25.12
Semaglutide treatment reduces heart failure risks
24.84
