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At ADA 2025, the SOUL trial revealed that oral semaglutide (Rybelsus) reduced the risk of major cardiovascular events—like heart attack, stroke, and CV death—by 14% over ~4 years in type 2 diabetes
26.70
Canadian Perspectives 2025 Whiteboard on the SOUL Trial
24.17
SOUL: Oral Semaglutide Bests Usual Care in High-Risk Type 2 Diabetes
26.13
In patients with cardiovascular disease and overweight or obesity but no diabetes, semaglutide was superior to placebo in lowering the risk of major adverse cardiovascular events at a mean follow-up of 39.8
21.67
Rethinking the Standard of Care:
22.88
ADA 2025: Oral Semaglutide Demonstrates Cardiovascular Benefits in SOUL Trial
29.69
Projected impact of oral semaglutide on cardiovascular outcomes over
20.93
