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In the SURMOUNT-4 trial, 82.5% of adults with obesity regained ≥25% of initial weight lost within one year of tirzepatide withdrawal; most showed reversal of cardiometabolic improvements. https://ja.ma/4qaMLfO
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A 72-week trial compared the two leading GLP-1 medications in adults with obesity (no diabetes). The results: ✓ Tirzepatide: 20.2% weight loss ✓ Semaglutide: 13.7% weight loss But weight loss isn't the
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Tirzepatide is redefining obesity & diabetes care. Dual GIP/GLP-1 action → deeper weight loss, stronger metabolic control, and emerging benefits from OSA to cardiometabolic risk. The era of multi-pathway incretin therapy has
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Thinking about stopping a GLP-1 medication?, Worried about weight regain?, Here’s what the SURMOUNT trial actually found…”, The SURMOUNT-4 trial looked at what happened when people stopped tirzepatide
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Shifts in body mass index category with tirzepatide and associated changes in cardiometabolic risk factors in people with obesity: a post hoc analysis from the SURMOUNT-1 and SURMOUNT-4 trials
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In the SURMOUNT-1 trial (published in NEJM in July 2022), adults with #obesity treated with weekly tirzepatide, a glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor
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SURMOUNT 1 // Three-Year Obesty & Diabetes Prevention Outcomes
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