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67,000 people on semaglutide (Wegovy) or tirzepatide (Mounjaro). 410,198 Reddit posts. Analysed by the University of Pennsylvania and published in Nature Health, April 2026. 43.5% reported at least one side effect. The
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side effects of Ozempic (semaglutide), a GLP-1 receptor agonist widely used for the management of type 2 diabetes mellitus and for weight loss. Common side effects—primarily gastrointestinal—include nausea, vomiting, diarrhea, constipation, abdominal
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