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Mast Cell Activation Syndrome (MCAS) can trigger widespread inflammation, allergies, and unexplained symptoms. GLP 1 medications, such as semaglutide and tirzepatide, may help calm things down. Safety worries spur Pfizer to drop another obesity pill BioPharma Dive The GLP 1 effect: Reformulating for high protein, nutrient packed demand How to Inject Semaglutide (Step by Step Guide for Weight Loss Injections)
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4.5 ★★★★★
Based on 1053 reviews
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Product Reviews
★★★★★ 5
My Rottweiler tries to get the extra large broke in half treat out for hours.
Size: Large (Pack of 1), Product Packaging: Standard Packaging
This is super tough and super great.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 4, 2026
★★★★★ 5
Great for Slowing Down Snack Time
Size: Large (Pack of 1), Product Packaging: Standard Packaging
My dog, an English Lab, is a voracious chewer, and destroys most toys in a matter of seconds. He also swallows most snacks without even chewing, and finishes meals in record time. It takes him about 20 minutes to get everything out of the Kong, and since I hide it somewhere on our property, he also takes several minutes to find it. He seems to really love the challenge, and it’s nice to have him take more time with a snack. I tried the Kong Easy Treat to seal the toy, but I find peanut butter works just as well (especially when frozen after being filled and sealed), and it’s cheaper and easier to use.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 12, 2026
★★★★★ 5
This product actually lives up to the title of indestructible.
Size: Large (Pack of 1), Product Packaging: Standard Packaging, Size: Large (Pack of 1), Product Packaging: Standard Packaging
This is the only toy I've had which my dog hasn't destroyed in minutes. I have had a few others that will at least last a few months, but Kong extreme has held up over the years. I like the fact that I can stuff it with treats, bits of other "indestructible" toys and seal it up with peanut butter, then pop it in the freezer to give her an extra 15 minute challenge. I have a couple so I can clean one while she's busy with the other. This size seems to be the best for a ~90lb. dog, the large end being roughly the same size as a tennis ball, which she loves as well.
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Reviewed in the United States on June 9, 2026
★★★★★ 4
Great product but choose a size or two up
Size: Large (Pack of 1), Product Packaging: Standard Packaging
Nice quality toy for long lasting and engaging play! One star docked for the sizing—I don't usually expect to need an xl anything for my 45lb border collie but he cant even fit his canine teeth into the large size to ease the jerky reward out in "hard" position but "easy" position he doesn't even tough the toy just grabs the jerky. Got an XL and it has been great for the jerky both easy and hard positioning. The larges I keep around for liquidy and frozen treats to keep the mess contained and they work very well for that.
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Reviewed in the United States on July 12, 2025
★★★★★ 5
Truly for Aggressive Chewers
Size: Large (Pack of 1), Product Packaging: Standard Packaging
Excellent product for aggressive chewers. The black Kong doesn't last forever BUT it is the most reliable toy I've used with my 60# pitt mix. I've returned so many toys that were advertised as for this girl's level of enthusiasm that I no longer buy anything else.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 12, 2026
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