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glp 1 and gip dual agonist Novel GIP + GLP-1 receptor dual agonist combined into a single drug dubbed a "twincretin," shows up to 2.4% reductions in HbA1c and nearly 25 pounds in weight loss in T2D patients

Marsoni M251S
Sale price$23.94
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Get it in 3 business days with 1 day shipping. Friday, May 29
Brand new research GLP 1 drugs may also fight addiction. In a study of 600,000 patients, people taking the medications had: 50% fewer substance related deaths 39% fewer drug overdoses GLP 1 change: State board drops coverage of obesity drugs Full article: Retatrutide: a triple incretin receptor agonist for obesity management GLP 1 Alcohol Cravings: How Ozempic Helps Quit Drinking
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4.4 ★★★★★
Based on 1910 reviews
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Product Reviews
D
Verified Purchase
David
Whiting, US
★★★★★ 1
It doesn’t even fit
It doesn’t fit our Breville Barista Pro because the portafilter head is too tall. Such a disappointment. Update: Absolutely horrible customer support as well. Their only attempt to rectify the situation was by double checking their own portafilter they have and confirming it works. It’s equivalent of “we investigated ourselves and found nothing wrong.” No replacements, no willingness to accept constructive criticism in order to change the dimensions slightly by decreasing the height of the portafilter head by even a millimeter to make it work, nothing. Just a slap in the face telling me to return it and be gone. Avoid this product.
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Reviewed in the United States on January 4, 2025
R
Ree
Dallas, US
★★★★★ 4
More work than it’s worth
It was great quality and the weight was nice, but it was odd having the open bottom and no spout to dribble into a cup when making an espresso. It was difficult to get the wire tool out of the end of the handle, making it difficult to use. I was not that impressed and it’s quite expensive.
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Reviewed in the United States on March 5, 2025
M
Verified Purchase
Mike Steven
Carnegie, US
★★★★★ 5
Quality and Function
Looks like a silly little thing, I am not a coffee enthusiast. But it does exactly what it is supposed to do and with high quality. The device (a stretch to call it that) is made of sturdy materials including the needles. They give you two different thicknesses of needles, one for expressi (0.3) and one set for coffee grinds (0.4). Each comes wth some spares. The stand is well designed and keeps grinds from spreading all over. It is very elegant design. I use this with a dosing funnel on my portafilter. Not the cheapest one could buy but well worth the money.
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Reviewed in the United States on March 16, 2025
S
Verified Purchase
Sunny
Alexandria, US
★★★★★ 5
Well made, high quality product.
This product demonstrates excellent quality, featuring a robust construction and intuitive design for ease of use. It includes two distinct wire sizes and offers straightforward assembly. Its superior durability and strong magnetic properties ensure effortless reattachment to its stand.
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Reviewed in the United States on June 30, 2025
A
Verified Purchase
Amazon Customer
Lowell, US
★★★★★ 5
Perfect WDT tool
Best WDT I’ve found. Love that it includes 0.3mm needles (as I’ve found that 0.4mm needles push the grounds around too much), and the stand is very clever. It knocks off the residual grounds on the needles and is easy to use. As far as WDT tools go, I can’t imagine anything better.
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Reviewed in the United States on April 13, 2025

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