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Now, a new world-first clinical trial reveals a safe, effective, and long-lasting way to maintain drug-free weight loss after GLP-1 discontinuation
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Research shows that weight often returns after stopping GLP-1 drugs like Ozempic and Wegovy. In the STEP-1 Extension Trial (published in Diabetes, Obesity and Metabolism), participants regained about two-thirds of the weight
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New real-world data show that over half of people who stop GLP-1 weight-loss drugs regain some weight within a year. The findings align with clinical trial data: once treatment stops, weight typically
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Stopping GLP-1 drugs can quickly erase cardiovascular benefits – WashU Medicine
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Stopping GLP-1s: Weight Regain and Maintenance Tips
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Two Years After Stopping GLP-1s, Most Patients Sustain at Least Some Weight Loss
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ISPOR 2025: Exploring reasons for GLP-1 discontinuation
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