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New Science Suggests Semaglutide Improves CV Outcomes Beyond Weight Loss
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A newly approved 7.2-mg dose of injectable semaglutide lowered weight by 3 percentage points more than the standard 2.4-mg dose in clinical trials. "No formal medical criteria have been established for escalating
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Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial
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The SELECT trial. Semaglutide 2.4mg. The headline: "20% reduction in major cardiovascular events." Here is what 20% actually means. The placebo group had an 8% event rate. The semaglutide group had a
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Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity
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❤️ Heart protection that works even without diabetes. The SELECT trial proved semaglutide 2.4 mg cut major cardiovascular events by 20% in people who had heart disease + overweight/obesity but no diabetes
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Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - Diabetes, Obesity and Metabolism
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