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Tirzepatide, Hormone Therapy Combination Increases Weight Loss in Postmenopausal Women
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Hormone Therapy May Boost Weight Loss on Tirzepatide A real-world study presented at ENDO 2025 found that menopausal hormone therapy (MHT) significantly enhanced weight loss in postmenopausal women using tirzepatide (Mounjaro, Zepbound)
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Postmenopausal women on the GLP-1 medication tirzepatide (Zepbound) for obesity lost more weight if they were also using menopause hormone therapy, a retrospective cohort study indicated. https://www.medpagetoday.com/endocrinology/menopause/119594
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