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Johannes Mann ending with a plug for the FLOW trial, the only dedicated renal outcome trial testing the effect of GLP1-RA (semaglutide) on a primary outcome of 50% decline in eGFR/ESKD/renal death #
28.56
FLOW trial Ozempic® (semaglutide injection)
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🔴Cardiovascular outcomes with semaglutide by severity of chronic kidney disease in type 2 diabetes: the FLOW trial⤵️ 🔹Semaglutide significantly reduced the risk of CV death/MI/stroke regardless of baseline CKD severity in participants
21.27
In the FLOW trial, researchers assessed whether the glucagon-like peptide 1 receptor agonist semaglutide was effective in preventing progression of kidney disease in patients with type 2 diabetes and chronic kidney disease
22.97
Effects of Once-Weekly Semaglutide on Kidney Disease Outcomes by KDIGO Risk Category in the SUSTAIN 6 Trial
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The FLOW trial (NEJM 2024) was the first dedicated renal outcomes trial of a GLP-1 receptor agonist. In 3,533 patients with type 2 diabetes and chronic kidney disease, semaglutide 1.0 mg weekly
29.23
FLOW Analysis: Semaglutide Delivers Consistent Kidney Benefit in T2D/CKD Across CVD Status
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