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GLP-1 is a metabolic hormone that acts in the brain to shape reward, motivation, and cognition — weight loss follows as a secondary outcome of central regulation. Currently, GLP-1 is marketed for
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Structural basis of peptidomimetic agonism revealed by small-molecule GLP-1R agonists Boc5 and WB4-24
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GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys
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Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists
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GIP/GLP-1
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The Multifaceted Nature of GLP-1: Molecular Mechanisms and Signaling Pathways in Metabolic and Neurodegenerative Diseases
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How GLP-1 Receptor Agonists Evolved from Diabetes to Weight Loss Treatments
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