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Weight loss isn't just about willpower, your hormones play a major role, especially during perimenopause and beyond. Even with GLP-1 medications, a hormone deficient state can make progress slower and more frustrating
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The GLP-1/GIP dual-receptor agonist tirzepatide led to at least 15% loss of total body fat in premenopausal, perimenopausal, and postmenopausal women, but postmenopausal women taking menopausal hormone therapy had the greatest weight
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